ABSTRACT
We report an unknown complication of peripherally inserted central venous catheter in a patient with Ventricular Assist Device. This rare complication led to the failure of the right ventricular assist device, which could be detrimental in patients with dilated cardiomyopathy.
Subject(s)
Adult , Cardiomyopathy, Dilated/surgery , Cardiomyopathy, Dilated/therapy , Catheterization, Central Venous/adverse effects , Device Removal , Equipment Failure , Gram-Negative Bacterial Infections/complications , Gram-Negative Bacterial Infections/therapy , Heart Transplantation , Heart-Assist Devices/adverse effects , Humans , Hypertrophy, Left Ventricular/surgery , Hypertrophy, Left Ventricular/therapy , Hypertrophy, Right Ventricular/surgery , Hypertrophy, Right Ventricular/therapy , Critical Care , Male , Stenotrophomonas maltophiliaABSTRACT
The pathophysiology of stroke is complex and involves an abnormal interaction between vessel wall and platelets. Of late many genetic and environmental factors impinging on the vessel wall have been identified which may determine the susceptibility of an individual to stroke. These include elevated homocysteine levels, chronic chalymydial and periodontal infection, plaque characteristics and genetic susceptibility. Intervention with HMG CO enzyme A reductase inhibitors, Angiotensin Enzyme Inhibitors and vitamins have been shown to offer protection.
ABSTRACT
Twenty-eight rhesus monkeys in 3 groups were exposed to single (Group I), double (Group II), and multiple (Group III) inoculations with B. malayi infective larvae. Infections were monitored by microfilarial and blood counts, selected biochemical tests, IFA responses, and records of body temperature and lymphadenopathy before and/or after treatment with DEC. As a whole, the highest microfilaraemia levels were observed in Group II and lowest in Group III monkeys. Eosinophilia was a common occurrence but reached the highest mean levels in Group III. Intermittent fevers and lymph node enlargements were observed in all groups of monkeys and the occurrence of these appeared to be correlated. No definite pattern of antibody production was discernable among groups, but an inverse relationship existed between microfilaraemia and detectable microfilarial antibodies. Treatment with DEC produced a microfilaraemia-taxic effect within the initial half hour and responses to treatment varied according to individuals. Although post-treatment reinfection appeared to cause lymphoid responses and tissue eosinophilia, no substantial resistance to reinfection was observed.